One of my favorite newish shows is The Big Bang Theory. It's about four very nerdy young scientist-types -- and their attractive neighbor. It's actually smart, and for this reason, I fear it may soon be canceled (this is perhaps irrational, as both 30 Rock and The Office are considered "smart.") I have no proof that it's in danger, mind you, just a feeling of impending cancellation.
Okay, there is one reason: Every time I ask someone if they watch the show, they think I am talking about "The Universe" on the History Channel. Not a good sign if you're trying to generate a buzz about a new show.