BREAKING: There's an Update on the Gag Order Against Trump
Sorry, Canada, the Stanley Cup Is Staying in the USA
Watch a British Journalist Annihilate Anti-Israel Clowns During a Debate Over Zionism
Australian Swimmer Who Trashed US Team Just Got Served a Piping Hot Cup...
Ernst Demands Pentagon Come Clean About Taxpayer Funding for Risky Research in China
Here's What D.C. Just Took Away From Hunter Biden
'Absurd and Shameful': Here's What Biden Is Allowing Iran to Do on American...
Russia Warns America to Expect Retaliation After Kyiv's Attack on Crimea With US-Supplied...
Conservative Legal Group Urges Election Officials Nationwide to Halt Non-Citizen Voter Reg...
Second Illegal Alien Suspect in Texas Girl's Murder Has Bail Set at $10...
Governor Newsom's Budget Agreement Could Cost Him His Run for Presidency
Fact Check: Biden Has Been Far Worse Than Trump on Deficits and Debt
New York County Passes Transgender Athlete Ban
Roe v. Wade Was Overturned Two Years Ago. Here's What Kamala Harris Said...
Some Advice for Trump Ahead of the Debate
Tipsheet
Premium

British Researchers Make Major Discovery That Has Potential to 'Kill Most Cancers from All People'

NCI Center for Cancer Research/NIH via AP

British scientists have stumbled upon a new type of immune cell that appears to kill most cancers, while leaving healthy cells alone.

Researchers at Cardiff University made the exciting discovering of the new T-cell when they were examining blood for an immune cell that could fight bacteria, igniting hopes of a “‘one-size-fits-all’ cancer therapy.”

“So we’ve found a new type of white blood cell that has the capacity to kill most cancers from all people,” says Cardiff University’s School of Medicine Professor Andrew Sewell in a video explaining the discovery. 


Conventional T-cells scan the surface of other cells to find anomalies and eliminate cancerous cells - which express abnormal proteins - but ignore cells that contain only “normal” proteins.

The scanning system recognises small parts of cellular proteins that are bound to cell-surface molecules called human leukocyte antigen (HLA), allowing killer T-cells to see what’s occurring inside cells by scanning their surface.

HLA varies widely between individuals, which has previously prevented scientists from creating a single T-cell-based treatment that targets most cancers in all people.

But the Cardiff study, published today in Nature Immunology, describes a unique TCR that can recognise many types of cancer via a single HLA-like molecule called MR1.

Unlike HLA, MR1 does not vary in the human population - meaning it is a hugely attractive new target for immunotherapies. (Cardiff University)

The discovery offers “'exciting opportunities for pan-cancer, pan-population” immunotherapies not previously thought possible,’” researchers said.

In the lab, the new treatment killed lung, skin, blood, colon, breast, bone, prostate, kidney, cervical, and ovarian cancer cells, while ignoring healthy cells.

“We hope this new TCR may provide us with a different route to target and destroy a wide range of cancers in all individuals,” said Sewell, lead author of the study.

“Current TCR-based therapies can only be used in a minority of patients with a minority of cancers,” he continued. “Cancer-targeting via MR1-restricted T-cells is an exciting new frontier - it raises the prospect of a ‘one-size-fits-all’ cancer treatment; a single type of T-cell that could be capable of destroying many different types of cancers across the population."

While much testing still remains to be done, the breakthrough is encouraging. 

“Previously nobody believed this could be possible,” Sewell said.

Recommended

Trending on Townhall Videos

Advertisement
Advertisement
Advertisement