Senior members of Aung San Suu Kyi's party are meeting to decide whether to register it as a legal body so that it can take part in future elections.
The National League for Democracy leaders, meeting in Yangon, are likely to approve the move now that the military-aligned government has lifted a restriction that had barred her from contesting.
The NLD refused to register last year because of that restriction. It was scrapped by the nominally civilian government that took office after winning the November 2010 elections.
The government's reforms have led to the United States softening its position on Myanmar after shunning it for decades. President Barack Obama announced Friday that he would send Secretary of State Hillary Rodham Clinton to Myanmar next month.