The Megabus.com transportation service is using Pittsburgh to bring service to nine new cities.
Company officials say Pittsburgh will be the hub for service to Erie; Detroit; Toronto; Buffalo, N.Y.; and Akron, Cincinnati, Cleveland, Columbus and Toledo in Ohio.
Pittsburgh already has service to New York; Washington, D.C.; and Philadelphia, Harrisburg and State College.
Seats can be booked starting Tuesday. Service will begin on May 11 with trips originating under the David L. Lawrence Convention Center.
Travelers who book well in advance can get one-way fares as low as $1.