Energy Secretary Steven Chu says Japan's nuclear crisis will influence the locations of new U.S. nuclear reactors.
He's suggesting that population might be a greater factor than it has been in deciding where to build a plant.
President Barack Obama has ordered a comprehensive review of U.S. nuclear plant safety.
New York Gov. Andrew Cuomo is seeking a review of the Indian Point power plant, about 40 miles north of New York City. More than 21 million people live within 50 miles of the plant.
Chu tells "Fox News Sunday" that officials believe Indian Point is safe, but they will review whether it should continue operating in the wake of the Japanese disaster.
Chu says decisions on where to site any future plants will be different than in the past.