(Reuters) - Peyton Manning broke the career touchdown pass record as the Denver Broncos thrashed the San Francisco 49ers 42-17 on Sunday.
With his third touchdown of the game late in the first half, the Denver quarterback notched his 509th regular season touchdown pass, surpassing the previous record held by Brett Favre.
Manning's record stole the show for the Broncos, who completely dominated the visiting 49ers to improve to 5-1 for the season and consolidate first place in the AFC West.
With victory assured, Manning left the game early after throwing a fourth touchdown and taking his tally to 510 with his fourth touchdown pass of the game to Demaryius Thomas, who had earlier caught the record-breaking 509th touchdown.
Manning completed 22-of-26 passes for 318 yards.
(Reporting by Andrew Both in Cary, North Carolina)