(Reuters) - The Chicago Bears scored 21 unanswered points in the fourth quarter to stun San Francisco 28-20 on Sunday, which spoiled the 49ers first game in their new billion-dollar stadium.
Jay Cutler tossed four touchdown passes, including three in the fourth, to help the Bears get their first win of the season.
After being down 17-0 in the second quarter and 20-7 in the third, Cutler found Brandon Marshall on a five-yard toss early in the final quarter to pull Chicago to 20-14.
Bears defensive back Kyle Fuller then intercepted a pass on San Francisco's next possession and Cutler put the visitors ahead 21-20 on a three-yard throw to Martellus Bennett.
Chicago capitalized on yet another interception from Colin Kaepernick when Cutler drove the team 42 yards and connected with Marshall again for the final score.
San Francisco drove down to Chicago's 17-yard line on their final possession but Kaepernick threw an incomplete pass on fourth down.
The 49ers quarterback passed for 248 yards and a touchdown, and ran for another 66 yards, but gave up three interceptions.
It was San Francisco's first game in their new stadium in Santa Clara after ending a long and successful tenure at Candlestick Park last season.
Chicago picked up just 216 yards of total offense.
(Writing by Jahmal Corner in Los Angeles; Editing by Greg Stutchbury)