Merck advancing breast cancer drug to mid-stage

AP News
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Posted: Dec 10, 2014 1:42 PM

KENILWORTH, N.J. (AP) — Drugmaker Merck & Co. says it will advance a new cancer drug into bigger patient tests, after promising findings in an early study against a very aggressive, common type of breast cancer.

Merck says its Keytruda (KEE'truh-duh) shrank tumors in one-third of patients, all of whom had triple-negative breast cancer that had spread. Most had worsened after multiple rounds of chemotherapy and other treatments.

The drug is in a hot new class of medicines, mostly still experimental, called immuno-oncology drugs. They harness the body's immune system to fight cancer.

Merck, based in Kenilworth, New Jersey, says it will start mid-stage patient tests of Keytruda in the first half of 2015. It's received accelerated approval for advanced melanoma and is being tested against five other cancer types besides breast cancer.