Summary Box: Actos hit first by safety warnings

AP News
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Posted: Aug 05, 2011 6:06 PM
Summary Box: Actos hit first by safety warnings

GROWING CONCERNS: Amid evidence that the world's best-selling diabetes drug, Actos, increases risk of bladder cancer, regulators in the U.S. and Europe are urging caution in using the drug. Sales have been stopped in Germany and France.

WAVE OF LAWSUITS: The drug's maker, Japan's Takeda Pharmaceuticals, faces hundreds to thousands of lawsuits from patients blaming Actos for their bladder cancer. Big law firms are advertising for clients.

PATIENT OPTIONS: Many doctors think patients should avoid Actos unless no other diabetes treatments help them control blood sugar enough.