What? An individual State could not survive without being attached to the huge centralized federal government? How about the Left-leaning Vermont separatists. As small as that State is they must be doomed. Why not do as you wrote above; "Let's see."
"Good luck with that...." The Federal government knows it can't survive without the States. See the great war "to save the Union," i.e. the Civil War. ("The Union" = The Tederal government, i.e. the Federal government is the entity which "Unites" the States.)