FILE - In this Tuesday Sept. 16, 2008 file photo, American murder suspect Amanda Knox is escorted by Italian penitentiary police officers from Perugia's court after a hearing, central Italy. Italian prosecutors have appealed to Italy's highest criminal court a decision throwing out the murder conviction against Amanda Knox and her former Italian boyfriend in the brutal slaying of a British student. Perugia prosecutors filed the 111-page appeal on Tuesday, Feb. 14, 2012, more than four months after an appeals court in Perugia threw out murder convictions against Knox and Raffaele Sollecito. Knox and Sollecito were convicted in a lower court of murdering Knox's British roommate in what prosecutors described as a sex-fueled attack. An appeals court said the evidence did not hold up. (AP Photo/Antonio Calanni, File)