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Friday, July 28, 2006
Paul Greenberg :: Townhall.com Columnist
The Frankenstein Syndrome
by Paul Greenberg
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It's a juicy prospect for a fast-developing industry: billions in federal grants for experimentation on human embryos.

Experienced grant writers must be revving up their search engines by now, since state grants for such research are already becoming available in states like Connecticut and Illinois and, of course, California, that bellwether of the surreal American future.

This session, Congress got behind this Next Big Thing, voting to expand embryonic stem cell research. But for the moment this rush to experiment on human embryos has been thwarted by a presidential veto, which the House failed to override.

But only for the moment. This is but a pause in the march of scientism, not a stop. After all, it's just one more slight little ethical boundary to be crossed on man's march toward physical and mental perfection, aka The Abolition of Man. That was the title of C. S. Lewis' percipient essay on the subject more than half a century ago.

Didn't this pro-life president himself authorize research on stem cell lines derived from already destroyed embryos? The moral of that story: One step down this slope quickly leads to another.

And yet George W. Bush balked at taking this latest one: "I felt like crossing this line would be a mistake, and once crossed we would find it almost impossible to turn back."

But wouldn't most of these discarded embryos be destroyed anyway? That's the standard argument offered in favor of embryonic research, and it opens up enough ethical questions to fill a talmudic treatise.

Yet all the rationalizations can't quite disguise the line that is being crossed here - for this time the embryos would be destroyed with the encouragement, indeed the monetary incentive, of the American taxpayer. That is, We the People. The ethical responsibility would be ours - not that of a fertility clinic and its clients.

The next ethical ridge to be crossed would then loom ahead: If it's permissible to experiment on embryos destined to be destroyed, why not on terminally ill patients, or prisoners on Death Row, or, well, the list would surely grow.

The case for embryonic experimentation isn't dubious just ethically but scientifically. To quote Robert P. George, a law professor at Princeton who served on the President's Council on Bioethics:

"Researchers know that stem cells derived from blastocyst-stage embryos are currently of no therapeutic value and may never actually be used in the treatment of diseases. . . . In fact, there is not a single embryonic stem cell therapy even in clinical trials. (By contrast, adult and umbilical cord stem cells are already being used in the treatment of 65 diseases.) All informed commentators know that embryonic stem cells cannot be used in therapies because of their tendency to generate dangerous tumors."

All of which leads Professor George to suspect that the clamor for embryonic stem cell research isn't really about using these early-stage blastocysts but exploiting more fully developed embryos, say those 16 to 18 weeks old, when the stem cells would be less likely to grow out of control.

Slate magazine's resident bioethicist, Will Saletan, outlined just such a program not long ago in his five-part series "The Organ Factory: The Case for Harvesting Older Human Embryos."

There's a short name for the kind of industry Mr. Saletan envisions: fetus-farming. Conclusion: Bioethics should never be confused with ethics.

The good news is that both houses of Congress also passed a bill - unanimously - that would outlaw the practice of growing embryos for scientific research. But how soon before that becomes the next taboo to be broken?

Embryonic research can also be challenged on economic grounds. Economists call it the problem of Opportunity Cost. That is, every dollar or million dollars invested in embryonic stem cell research cannot be invested in other forms of research. For example, research using stem cells derived from umbilical cord blood or the placenta. That kind of science offers considerable promise. And no ethical problems.

Yet the enthusiasts for embryonic stem cell research tend to oppose more federal support for research involving adult stem cells, and also funding for programs to develop stem cells without destroying human embryos in the process.

A bill embodying both aims was just defeated in the House - even as a majority of its members voted to support research using human embryos.

Embryonic research and embryonic research alone has become the cause du jour of the scientific and entertainment industry.

Given the choice between the ethically prudent course and going where no man has gone before, or dared to go, there is something in man that cannot resist the oldest temptation: Eat of this Tree of Knowledge and ye shall be as gods! No matter what false hopes may be raised, no matter what ethical boundaries crossed. Call it the Frankenstein Syndrome.

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Dead right!
This column is dead right, and it points out that this is just a part of the culture of death that we are seeing arise today. If it is okay to kill a fetus to harvest the stem cells, what comes next? Will it be okay to kill grandma off to get her corneas since she's near the end of her life anyway? The first step has been taken and we are going to have to fight like the dickens to keep from being pulled totally down that slope!

Crossing the line
The Ph.D.'s and M.D.'s in the labs at Auschwitz kept very detailed records that met every standard of science (save the piddling detail of subject consent). Their "research" might have provided valuable information, for example in human response to non-lethal trauma. And yet for years the scientific establishment in the civilized world refused to touch them. Why? Because nothing that could be learned would be worth crossing that line.

But, that was when science in this country was still even slightly guided by a vague memory of our Judeo-Christian heritage. Aren't we all glad we've "moved on?"

SLOPE
This issue appears to be following the same trajectory as the abortion debate. There, we've safely negotiated the "late term" barrier, and "post natal" abortions beckon just over the horizon.

Won't be long.

Re: ajhil's post
Amen, brother. I agree with everything in your post. I was going to try to post on this issue, but you beat me to it. And in a way that I could never be as articulate as you were. Adult stem cells are so "successful" because they only are used to treat a narrow range of diseases. The potential of pluripotent embryonic stem cells has not been realized because of lack of research, in my humble opinion. Fact remains, private funding is usuall only directed at therapies that show some promise. That's all well and good. ESC research only needs a breakthrough in human trials to get private funding. I believe there have been some successes in animal trials. You can smack me down and call me stupid if this is not the case. I do agree that the public should not be forced to fund experimentation that it finds offensive. However, I am also offended that the President vetoed a bill that the public's elected representatives passed. To me, that is the height of arrogance. "Y'all want it, but I don't," seems to be the President's mentality. Who does the President work for? Himself, or the People of the United States? Now, I'm all for limiting federal spending. God knows our government spends enough on lost causes. Why can't we spend a fraction on something that might actually help people instead of kill people? As for the anencephalic baby that was delivered, that is always a tragic event. If some benefit from such an event can be derived, we are remiss in not exploring what possible benefits may be gained. Just a few thoughts.

screeb

Stem Cell Rearch
Responding to Ajhil's somewhat antagonistic comments (do you ever just state your cause without putting people down?), it must be nice to have the font of all knowledge. I would not attempt to argue with you point by point since you do have a great deal of technical knowledge, which I admire. However, all your put-downs leave me pretty cold. And, the one thing you fail to address is, regardless of the potential efficacy of embryonic stem cells, which you admit have yet to yield any definite uses, if there were real potential for this to happen, wouldn't private sources with necessary funds to yield all the wonderful POTENTIAL embryonic stem cell cure-alls be coming? One thing you can count on from private industry, when there are profits to be made, they will move heaven and earth to make them, including use of embryonic stem cell research. That they're not, seems to answer the question for now. Pretty clearly G.W. Bush has correctly made the decision to veto the bill to pay for the research for funding of embryonic stem cells using OUR tax money, since even a liberal reading of the use of embryonic stem cells represents destroying a potential human life. Your arguments about the narrow successes of adult stem cells is something I can' argue with. Point well taken. But the narrow success of adult stem cells doesn't signal the definite success of embryonic stem cells in curing the diseases our Hollywood friends are touting. I still maintain if there is so much potential using embryonic stem cells, why hasn't private industry gone after such research? Has to be because they're doubtful of success. Probably secondarily, the moral issue bothers them? Still, potential profit would overcome that, I'd think.

To uwcharlie:

You’re right: one should remain civil in debates. You’re hjn9justified in chiding me for my abrasive tone in my last post. But have a look at the post from DocNoleCat, who not very subtly compares people in my camp to Nazi vivisectionists. This is the modus operandi of right wing Republicans, who have picked up the issue of abortion as a useful campaign tool.

If you’ve followed the resulting debates at all, then you’re aware of the way in which people like me who favor abortion rights have been characterized. If you know much about medicine and the way it’s actually practiced in the real world, you also know that “late term” abortions are quite rare and are performed, if at all, for very good medical reasons. The anencephalic birth I described is a typical example of a delivery that should have been terminated that way.

As a physician, I’m offended, when I’m accused of being careless of human life. I’m even more deeply offended, when the people who make the accusations do so on the basis of ignorance and misinformation.

Regarding your other point about private research, you’re right: corporations need a substantial profit motive to spend money on basic research. They also need to have substantial resources to begin with. Pharmaceutical companies like Merck and others with their enormous sales base and huge profits still find it necessary to have federal aid to conduct much of their research. It’s just that expensive! Furthermore, there is no guarantee that a given therapy or product will ever be approved and produce a profit; most don’t! Of the small, start-up med-research companies that conduct stem-cell research, how many do you think could afford this level of outlay, not to mention risk? How many could survive the failure of an important project? Only the federal government has the immensely deep pockets required for modern medical research. It has very little to do with the prospects for profit.


Taxable Ethics
When are we going to have a Conservative writer on Townhall.com talk about crossing the Ethical Boundary in TAKING TAXPAYER DOLLARS to pay for something THE GOVERNMENT HAS NO BUSINESS PAYING FOR?

This is just taxing Peter to pay Dr. Paul. Don't we have an ethical boundary we're not supposed to cross here? No matter whether the Dr. Paul's planned use is going to be "benign" or "beneficial" or "useful" or "Awe-Inspiring", isn't it still unethical to use tax money for that purpose?

If we're going to use tax dollars that we take from citizens by force, shouldn't that at least be for something explicitly provided for in the Constitution? The Contract that our Government has with the People?

Or have we gone so far down that "slope" until no one even remembers what the Constitution looks like anymore? Are we so far gone until the discussion will forever more be limited to WHICH wonderous awe-inspiring projects are worthy of our hard-won tax dollars? Instead of WHETHER we should be taxpayer-funding ANY sort of research?
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